SrasV1, Main, Exploration, bibRecord, 006408

Development of a standard treatment protocol for severe acute respiratory syndrome

Identifieur interne : 006408 ( Main/Exploration ); précédent : 006407; suivant : 006409

Development of a standard treatment protocol for severe acute respiratory syndrome

Auteurs : Loletta K-Y So [Hong Kong] ; Arthur C. W. Lau [Hong Kong] ; Loretta Y. C. Yam [Hong Kong] ; Thomas M. T. Cheung [Hong Kong] ; Edwin Poon [Hong Kong] ; Raymond W. H. Yung [Hong Kong] ; K. Y. Yuen [Hong Kong]

Source :

Lancet : (British edition) [ 0140-6736 ] ; 2003.

RBID : Pascal:03-0295939

Descripteurs français

Pascal (Inist)
- Détresse respiratoire adulte syndrome, Homme, Coronavirus, Protocole thérapeutique, Traitement, Ribavirine, Antibactérien, Association médicamenteuse, Méthylprednisolone, Chimiothérapie, Ventilation assistée, Hong Kong, Efficacité traitement, Corticostéroïde.
Wicri :
- geographic : Hong Kong.
- topic : Homme.

English descriptors

KwdEn :
- Adult respiratory distress syndrome, Antibacterial agent, Assisted ventilation, Chemotherapy, Coronavirus, Corticosteroid, Drug combination, Hong Kong, Human, Methylprednisolone, Ribavirin, Therapeutic protocol, Treatment, Treatment efficiency.

Abstract

A series of 31 patients with probable SARS, diagnosed from WHO criteria, were treated according to a treatment protocol consisting of antibacterlals and a combination of ribavirin and methylprednisolone. Through experience with the first 11 patients, we were able to finalise standard dose regimens, including pulsed methylprednisolone. One patient recovered on antibacterial treatment alone, 17 showed rapid and sustained responses, and 13 achieved Improvement with step-up or pulsed methylprednisolone. Four patients required short periods of non-invasive ventilation. No patient required Intubation or mechanical ventilation. There was no mortality or treatment morbidity in this series.

Affiliations:

Hong Kong

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000981
to stream PascalFrancis, to step Curation: 000010
to stream PascalFrancis, to step Checkpoint: 000971
to stream Main, to step Merge: 006920
to stream Main, to step Curation: 006408

Le document en format XML

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<term>Chemotherapy</term>
<term>Coronavirus</term>
<term>Corticosteroid</term>
<term>Drug combination</term>
<term>Hong Kong</term>
<term>Human</term>
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<term>Protocole thérapeutique</term>
<term>Traitement</term>
<term>Ribavirine</term>
<term>Antibactérien</term>
<term>Association médicamenteuse</term>
<term>Méthylprednisolone</term>
<term>Chimiothérapie</term>
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<front><div type="abstract" xml:lang="en">A series of 31 patients with probable SARS, diagnosed from WHO criteria, were treated according to a treatment protocol consisting of antibacterlals and a combination of ribavirin and methylprednisolone. Through experience with the first 11 patients, we were able to finalise standard dose regimens, including pulsed methylprednisolone. One patient recovered on antibacterial treatment alone, 17 showed rapid and sustained responses, and 13 achieved Improvement with step-up or pulsed methylprednisolone. Four patients required short periods of non-invasive ventilation. No patient required Intubation or mechanical ventilation. There was no mortality or treatment morbidity in this series.</div>
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Development of a standard treatment protocol for severe acute respiratory syndrome

Development of a standard treatment protocol for severe acute respiratory syndrome

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri